The Brain and Biomarker Laboratory (BABL), under the direction of Dr. Lauren Ethridge, is a multidisciplinary, translational neuroscience laboratory focusing on applications of basic science to clinical outcomes, particularly in neurodevelopmental disorders.
The BABL group centers on the use of dense-array EEG as a translational tool for learning more about brain function in neurodevelopmental disorders. The ultimate goal of our research is to establish non-invasive biological markers for changes in brain function that not only elucidate neural and molecular pathways affected by disorders such as Autism Spectrum Disorder (ASD) and but also serve as aids for early identification, early predictors for response to individualized treatment protocols, and reliable indicators of treatment effects.
Research in the lab is highly collaborative, with a large network of investigators across the country. Current research includes:
- EEG as a translational, treatment sensitive, biomarker in rare genetic disorders associated with autism and intellectual disability, including Fragile X Syndrome and Phelan-McDermid Syndrome
- Sensory processing disorders
- Characteristics of EEG activity related to variation in ASD symptoms across the full spectrum
- Neural correlates of child well-being and adverse childhood experiences